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Clinical Trials

What are pharmacokinetic studies?

These are studies designed to identify and describe one or more of the following basic pharmacological concepts in humans: absorbtion; distribution; metabolism and excretion, of drugs. These may be either stand alone studies, or incorporated into main clinical protocols. CCLG Centres wishing to participate in pharmacokinetic studies will need to have a research nurse in post, as it is the research nurse who is involved in sampling and form completion for these studies.

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  1. Introduction
  2. What is a Clinical Trial?
  3. Clinical Trial procedure
  4. The role of the Chief Investigator
  5. The Protocol
  6. How is the size of a clinical trial determined?
  7. What is a multi-centre trial?
  8. Role of coordinating centre/Trials Unit
  9. What is randomisation?
  10. How is a patient randomised for a particular trial?
  11. What is a control in clinical trials?
  12. Forms and data management
  13. Statistics in clinical trials
  1. The role of the trial coordinator
  2. Follow up
  3. How is the trial data analysed/evaluated?
  4. What are pharmacokinetic studies?
  5. Ethical issues
  6. Conduct of Clinical Trials/Research
  7. What is a blind trial?
  8. Interpretation and publication of findings
  9. Survival Curves
  10. UKCCSG Protocols – development and approval process
  11. References
  12. Download PDF
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